CONFERENCEProject title: Advancing personalized modeling of neuro-cardiac dysfunction using hiPSCs, CRISPR/Cas9, microfluidics, and MXene fiber technologies – NeuroCardioChip
Contract Number: ES RTD/…
Project coordinator: Albano MELI, Institut National de la Santé et de la Recherche Médicale, Francija
Project partners:
Viktoriia KORNIIENKO, University of Latvia, Latvija
Coy EMERSON, Adam Mickiewicz University, Polija
Cecilia FERRANTINI, NanoCarbonTech LLC, Polija
Collaboration partner: Oleksiy GOGOTSI, Università di Firenze, Italy
Implementation time: 2026 - 2029 (36 months)
Total project funding: … EUR
University of Latvia funding: 300 000 EUR, State budget
Research coordinator: Dr. Viktoriia Korniienko (Advanced Biomaterials and Biophysics Laboratory)
Administrative manager: Inga Šīrante, FST project manager
Project Abstract:
NeuroCardioChip is developing a specialized lab-on-a-chip system that mirrors real human biology using several advanced technologies:
- Human Induced Pluripotent Stem Cells (hiPSCs): Real patient stem cells are grown into interacting human heart and nerve cells.
- CRISPR/Cas9: Gene-editing technology is utilized on the chip to correct or study precise genetic mutations.
- Microfluidics: Advanced fluid channels mimic natural blood flow across the artificial biological tissues.
- MXene Fiber Technologies: A highly conductive nanomaterial is integrated to send and measure precise electrical signals between the heart and brain cells