Project title:

Advanced Spectral Imaging Technology for Skin Diagnostics

Project contract number:

lzp-2018/2-0006

Project implementation deadline:

01.12.2018 – 31.11.2020

Total project funding:

199 906,00 EUR

Research manager:

prof. Jānis Spīgulis (Biophotonics laboratory)

About the project:

This multidisciplinary project concerns the application of optical technologies in medicine. The project plans to adapt a proprietary technology that provides single-pinch monochromatic spectral imaging at multiple wavelengths (SMSLI – Snapshot Multi-Spectral-Line Imaging) to adapt skin neoplasm for contactless diagnostics. A new prototype device that will rapidly (<2s) capture 4 monochromatic skin images at different wavelengths as well as skin fluorescence image at 405 nm excitation will be developed and clinically tested. The image analysis software will allow operative mapping of the distribution of the 4 major skin chromophores and facilitate identification of neoplasms (including skin cancers). Expected impact on society – improved healthcare.

Projekta rezultāti: 

Plānotie rezultātu ietekmes indikatori:

Skaits

Zinātniskās publikācijas, kas indeksētas SCOPUS, WoSCC un/vai ERIH+

3

Intelektuālā īpašuma nostiprināšana (patenta pieteikums)

1

Dalība starptautiskās zinātniskās konferencēs vai to organizēšana

5

 

Sasniegtie rezultāti:

  • Publikācijas (SCOPUS, WoSCC un/vai ERIH+):
  1. J. Spigulis, I. Oshina, P. Potapovs, K. Lauberts, “Snapshot multi-spectral-line imaging for applications in dermatology and forensics”, Proc.SPIE, 10881, 1088114 (2019).                      
  2. J. Spigulis, I. Oshina, M. Matulenko, “Laser illumination designs for snapshot multi-spectral line imaging”, OSA Technical Digest, CLEO-Europe, cl_3_4 (2019), https://www.osapublishing.org/abstract.cfm?uri=CLEO_Europe-2019-cl_3_4.
  3. J. Spigulis, Z. Rupenheits, M. Matulenko, I. Oshina, U. Rubins "A snapshot multi-wavelengths imaging device for in-vivo skin diagnostics", proc. SPIE, 11232,112320I-1 (2020).
  4. J. Spigulis, Z. Rupenheits, U. Rubins, M. Mileiko, I. Oshina "Spectral Line Reflectance and Fluorescence Imaging Device for Skin Diagnostics", Q1 līmeņa publikācija (2020), https://www.mdpi.com/2076-3417/10/21/7472/pdf 
  5. J.Spigulis, I.Kuzmina, I.Lihacova, V.Lukinsone, B.Cugmas, A.Grabovskis, E.Kviesis-Kipge, A.Lihachev,  “Biophotonics research in Riga: recent projects and results”, Proc. SPIE 11585, 1158502 (2020).
  6. J.Spigulis, V.Lukinsone, I.Oshina, E.Kviesis-Kipge, M.Tamosiunas, A.Lihachev, "Recent Results of Riga Group on Laser Applications for Skin Diagnostics", J.Phys.: Conf. Series (2020, accepted).
  • Patents
  1. LV patenta pieteikums # P-19-45, 21.08.2019. “Ierīce virsmas vienmērīgai apgaismošanai vienlaikus ar vairākām lāzeru spektrāllīnijām”, autori J.Spīgulis, I.Ošiņa, Z.Rupenheits, M.Matuļenko.
  2. LV patents piešķirts 20.09.2020. patentu reģistrā ar Nr. LV15491
  • Dalība starptautiskās konferencēs:
  1. SPIE Photonics West / BIOS’2019, Sanfrancisko (ASV), 2019.g. 2.-7. februārī.
    Mutisks referāts: “Snapshot multi-spectral-line imaging for applications in dermatology and forensics”
  2. CLEO-Europe, Minhene (Vācija), 2019.g. 23.-27. jūnijā.
    Mutisks referāts: “Laser illumination designs for snapshot multi-spectral-line imaging”.
  3. Multiforesee 2019, Katānija (Itālija), 2019.g. 16.-18. septembrī.
    Mutisks referāts: “Multi-spectral-line imaging for forensics: recent developments”.
  4. Advanced Laser Technologies 2019, Prāga (Čehija), 2019.g. 15.-20. septembrī
    Mutisks ielūgtais referāts: “Lasers for skin diagnostics – chromophore mapping and photon path length estimation”.  
  5. SPIE Photonics West / BIOS’2020, Konference "Multimodal Biomedical Imaging", Sanfrancisko (ASV), 2020.g. 1. – 6. februārī.
    Mutisks referāts: “A snapshot multi-wavelength imaging device for in-vivo skin diagnostics”.
  6. Biophotonics – Riga 2020 , 2020.g. 24.-25. augustā, Rīga (Latvija)
    Mutisks referāts: ““Biophotonics research in Riga: recent projects and results”.
  7. International Conference and School on Quantum Electronics, ICSQE-212020.g. 21.-24.septembrī, Varna (Bulgārija)
    Mutisks ielūgtais referāts: “Recent Results of Riga Group on Laser Applications for Skin Diagnostics".